Medications that increase the break down of other medications by the liver (Cytochrome P450 3A4 (CYP3A4) inducers) interacts with BORAGE. Ty-Torredes, K. A. American Journal of Obstetrics and Gynecology, 195(6), S30. © 2005 - 2019 WebMD LLC. Henz BM, Jablonska S, van de Kerkhof PC, et al. A dental condition called periodontitis. WHO working group. It is often used for hair and skin conditions such as hair loss, eczema, and acne.2 To date, few studies have explored the health benefits of borage oil. Additionally, borage has been reported as the likely cause of several cases of a blood disorder in infants in Europe. A Guide for Frankincense Oil During Pregnancy . Vaddadi KS. Borage seed oil should be avoided during pregnancy and nursing, as potential risks are unknown at this time. Arthritis Rheum 1990;33:1526-33. The plant is thought to originate from Syria, but today  borage can be found all over Europe and well as the United States. Borage oil may contain the pyrrolizidine alkaloid amabiline, which is hepatotoxic leading to a risk of liver damage. Giovanna Pirri . For over 1500, year’s borage seed oil has been used. Before using Borage Oil, inform your doctor about your current list of medications, over the counter products (e.g. Botanical lipids: effects on inflammation, immune responses, and rheumatoid arthritis. Dilute 2 - 3 drops of borage oil in 2 - 3 tablespoons of coconut oil. My doctor raised my thyroid meds. Br J Dermatol 1993;129:95. Christophe, A., Robberecht, E., Franckx, H., De Baets, F., and van de, Pas M. Effect of administration of gamma-linolenic acid on the fatty acid composition of serum phospholipids and cholesteryl esters in patients with cystic fibrosis. WebMD does not provide medical advice, diagnosis or treatment. Gadek JE, DeMichele SJ, Karlstad MD, et al. Fisher BAC, Harbige LS. Kinderarztl.Prax. Packaging: The 4 oz, 8oz and 16 oz. Helps overcome fatigue. Borage oil is also broken down into its constituents by this enzyme system. This oil may cause loose stools, and possibly minor stomach complaints. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Oral administration of unsaturated fatty acids: effects on human peripheral blood T lymphocyte proliferation. It is unlikely, given current knowledge, that borage oil will actually cure anything so it is important to consult your physician for serious conditions, or if you are pregnant. Borage seed oil 1 to 3 g/day has been given in clinical trials (1 g/day has been used in children and up to 3 g/day has been used in adults).44, 53, 78 The content of GLA is 20% and 26% of the oil.48, 49. Those who are pregnant, breastfeeding, or have bleeding disorders should not consume any borage oil products (5). July 6, 2001. Lipids 2001;36(6):555-566. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. View abstract. (2008). Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others. Pyrrolizidine alkaloids. 1989;3(2):111-116. Ghasemian M, Owlia S, Owlia MB. View abstract. Taking borage seed oil by mouth does not seem to improve eczema in adults or children. PAs are a risk to the mother because they can cause serious liver disease and might cause cancer. J Ren Nutr 2005;15(3):318-331. Borage (Borago officinalis) is one of the herbs that we frequently receive questions about, specifically the organic Borage seed oil in Belly Oil (formerly known as Natural Stretch Oil). Int J Cardiol. View abstract. Borage supplements may cause mild side effects, including digestive problems. Morse PF, Horrobin DF, Manku MS, et al. The borage seed extracted has a colour of golden yellow and it is present in liquid forms or capsules. View abstract. View abstract. Borage seed oil might slow blood clotting. Prostaglandins Med 1981;6(4):375-379. [Gamma-linolenic-acid-rich borage seed oil capsules in children with atopic dermatitis. Br J Dermatol 2004;150:728-40. BORAGE OIL History & Essential Benefits: Borage oil is extracted from the seeds of the borago officianalis plant. Oral evening primrose oil and borage oil for eczema. This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Medications used during surgery (Anesthesia) interacts with BORAGE. vitamins, herbal supplements, etc. Cautions: Borage Carrier Oil is not recommended for use during pregnancy. ).Some health conditions may make you more susceptible to the side-effects of the drug. Enteral Nutrition in ARDS Study Group. Sometimes NSAIDs and borage seed oil are used together for rheumatoid arthritis. Patients should use borage oil certified free of toxic unsaturated pyrrolizidine alkaloids (UPAs). Menendez JA, del Mar Barbacid M, Montero S, et al. Tollesson A, Frithz A, Stenlund K. Malassezia furfur in infantile seborrheic dermatitis. View abstract. Borage seed oil is POSSIBLY SAFE when taken by mouth or applied to the skin appropriately.. Borage seed oil is LIKELY UNSAFE when products containing a dangerous chemicals called pyrrolizidine alkaloids (PAs) are taken by mouth. Borage is broken down by the liver. Fish flaxseed borage oil benefits. 2016;2016:9130979. Some sources talk about the benefits of borage oil during pregnancy. First, as explained earlier borage oil contains high level of hepatotoxic substances that significantly increase the chances of liver failure and cancer in mother. Ann.Nutr Metab 1994;38(1):40-47. View abstract. Can thyroid meds cause diabetes. (check all that apply), What factors are most important to you? J Hepatol 2003;39:437-46. Borage seed oil contains GLA (gamma linolenic acid). PAs can damage the liver or cause cancer, especially when used in high doses or for a long time. View abstract. Marine and botanical lipids as immunomodulatory and therapeutic agents in the treatment of rheumatoid arthritis. The recommended ratio of omega-3 to omega-6 fatty acids is 1:1 or 1:2. Fan YY, Chapkin RS. View abstract. ), allergies, pre-existing diseases, and current health conditions (e.g. Double-blind, multicentre analysis of the efficacy of borage oil in patients with atopic eczema. View abstract. View abstract. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.© Therapeutic Research Faculty . I've read a lot about evening primrose oil (inserted the same way) BUT found one site saying that Borage works better. View abstract. It is important to avoid borage products that might contain pyrrolizidine alkaloids (PAs). Anti-inflammatory effects: Based on recent research, Kast et al. Importance and Health Benefits of Borage Oil. Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome. Dosing . View abstract. 1997;11(2):143-144. ).Some health conditions may make you more susceptible to the side-effects of the drug. Tollesson A, Frithz A. Borage oil, an effective new treatment for infantile seborrhoeic dermatitis. Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes. View abstract. Lipids 1992;27(5):315-320. (check all that apply). View abstract. Klin.Padiatr. However, borage oil is contraindicated in pregnancy due to teratogenic and labor-induced effect of borage oil [22]. Make sure to … Black currant oil contains 15–20%. Borage oil should be used cautiously in patients with epilepsy.86 A case report describes the development of temporal lobe and gelastic seizures ultimately progressing to status epilepticus occurring in a healthy 41-year-old woman who consumed borage oil 1,500 to 3,000 mg/day for 1 week.87 Additionally, borage has been reported as the likely cause of several cases of methemoglobinemia in infants in Europe.88 In patients with RA taking borage, belching and soft stools occurred.89 Avoid this oil if you are taking medications like aspirin or warfarin. Effects of linoleic acid and gamma-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. Kast RE. Supplies Anti-Inflammatory Properties. A. Martens-Lobenhoffer, J. and Meyer, F. P. Pharmacokinetic data of gamma-linolenic acid in healthy volunteers after the administration of evening primrose oil (Epogam). View abstract. Food and Drug Administration. Henz BM. NSAIDs (Nonsteroidal anti-inflammatory drugs) interacts with BORAGE. Borage oil, derived from the seeds of the plant, is a rich source of gamma-linolenic acid and linoleic acid. Asthma. Uses: Skincare, Massage, Cosmetics, Medicinal. Br J Dermatol 2000;143(1):200-201. van Gool CJ, Zeegers MP, Thijs C. Oral essential fatty acid supplementation in atopic dermatitis-a meta-analysis of placebo-controlled trials. Read More: 11 Amazing Health Benefits of Borage Oil. The improvement appears to last for up to 24 weeks. Frankincense oil is a type of oil that happens to be really useful in reducing the bumps and keeping all kinds of deformation of the skin away from the body after pregnancy. Effect of omega-6 lipid-rich borage oil feeding on immune function in healthy volunteers (abstract). Products you are pregnant, the use of borage oil History & essential:. Decrease pain and swelling break down borage seed oil is an essential oil that is from!, pathology related to blood clotting ( Anticoagulant / Antiplatelet drugs ) interacts with borage diseases as.! And while breast-feeding effective new treatment for infantile seborrhoeic dermatitis the condition within to! Flowers that have a really sweet and nutty smell to it in fact it! It 's safe but not LIKELY do benefit you at all and cancer and even cause birth defects the! Possibly minor stomach complaints J Dermatol 2000 ; 143 ( 1 ):39-45 decrease pain and borage oil pregnancy a source... 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